UNDER CONSTRUCTION

This website is dedicated to Sidney M Baker.

The goal of this website is to show that bacterial toxins can induce many chronic conditions and diseases. This gives us the hope that someday SCD might be used to heal many chronic conditions. This will be possible because one man, Sidney M Baker, had the courage to make SCD accepted as one of the official diets for autism. This was the first time in over 50 years that SCD had gotten official recognition after years of being neglected and scorned by the medical establishment. Dr. Baker's dedication might inspire other doctors to follow his steps and will open the door to the medical use of SCD for many other conditions.

Can bacterial toxins induce most chronic illnesses?

Scientists from all over the world have found that bacterial toxins, especially LPS, play a central role in diseases of inflammation. Most chronic diseases of affluence are diseases of inflammation and they include diabetes, heart disease, arthritis and even certain forms of cancer.

LPS, a very common bacterial toxin, has been implicated for playing a key role in auto immunity and most other diseases of inflammation. LPS is ubiquitous [1] and one of the most potent agents for inflammation.[2] The July 2007 issue of Scientific American has an article about the exciting link between cancer and inflammation.[4] The article mentions that chronic infection from bacterial sources can trigger cancer.[4] Even the scientists working for the FDA have found a link between bacteria and cancer.[5] The abstract of the article mentions that bacteria and other factors can trigger cancer.[5] The full article discusses the role of LPS. [5] This website contains research articles that demonstrate how LPS is capable of inducing many diseases of inflammation.

Why are children with autism more likely to get the chronic diseases that are induced by LPS?

Children with autism have a very high risk for getting colorectal cancer.

ASD children are very EXTREMELY vulnerable to LPS for the following reasons:

1 Children with ASD have incredibly high levels of LPS. Rosseneu found that 94% of 80 children with regressive autism and chronic constipation/diarrhea had approximately 10,000-fold higher than normal levels of E. coli in their stool.[6]( E. coli are gram negative bacteria that have LPS. )

2 Results of scientific investigation indicate that most ASD children produce an excessive, innate immune response to LPS. [7]. Scientists have found that the immune responses to LPS are more harmful than the bacterial toxin itself.[3]

The Vegan diet has been promoted as a diet for the prevention of chronic disease. What commonality do SCD and the vegan diet share that leads to the reduction of LPS?

Both diets lead to higher consumption of vegetables,fruits and nuts; both diets avoid the lactose from cow's milk. The Vegan diet and the SCD diet lead to a higher intake of fruits,nuts, and vegetables since these diets have so many other food restrictions. The increase of fruits and vegetables results in an increase in antioxidants. Scientific articles show that phenolic antioxidants inhibit the induction of some of the inflammatory cytokines produced by LPS. [8] Some scientists believe that the reason antioxidants help prevent cancer might be due to their suppression of the inflammation caused by LPS.[9]

Nuts are also very beneficial for health. �Nut consumption seems to protect against ischemic heart disease (IHD). Moreover, frequency of nut consumption has been found to be inversely related to all-cause mortality. Thus, nut consumption may not only offer protection against IHD, but also increase longevity.[10] Nuts contain antioxidants as well as alpha linolenic acid acid.[11] One research article suggests that alpha linolenic acid supplementation may be an aid in the prevention of endotoxemia (LPS poisoning) in horses.[11] Another research study shows that alpha linolenic acid inhibits the proinflammatory cytokines induced by LPS.[12]

Why would the lactose from cow's milk be so risky? Lactose malabsorption is the most vulnerable and common type of carbohydrate malabsorption.[13] Unabsorbed carbohydrates provide food for gut pathogens; these gut microorganism then overgrow and emit toxins that can induce disease.

Why would SCD be a better diet for the prevention of chronic disease and LPS?

The vegan diet does not help people who have a vulnerability to other forms of carbohydrate malabsorption besides lactose. Unfortunately, some people with ASD have an inability to digest the other types of difficult-to-digest carbohydrates. Campbell does not list, autism, carbohydrate malabsorption nor GI disorders as conditions that are helped by the vegan diet. Nowhere in Cambell's book is there any mention of veganism as helping GI disorders despite the fact that GI disorders are one of the most common chronic diseases of the west. Anecdotal evidence indicates that the vegan diet might actually promote GI problems.

Since most chronic diseases are due to dysbiosis, it appears wise to avoid eating carbohydrates that are difficult to digest. Eliminating lactose alone would solve the problem for many. However, this might not be sufficient as some people are vulnerable to other types of carbohydrate malabsorption and need to limit additional "difficult to digest" carbohydrates. While the Vegan Diet only protects from lactose, SCD eliminates both lactose and all the other difficult to digest carbohydrates.

The Pecanbread version of SCD appears to be the best diet for the elimination of LPS and chronic disease for the following reasons:

1 SCD is the only diet that is very strict about eliminating all the difficult to digest carbohydrates. The Vegan diet allows an unlimited amount of starches. There is a subgroup of ASD children who cannot absorb starches and other complex carbohydrates even after several years of doing SCD. They might not show negative symptoms right way but may develop problems later on.

2 The SCD goat yogurt is an incredibly powerful food for fighting both cancer and LPS.

Scientific studies show that some of the constituents of milk such as whey have anti-carcinogenic properties. Whey protein is superior to other dietary proteins for suppression of tumour development.[14] This benefit is attributed to its high content of cystine/cysteine and gamma-glutamylcyst(e)ine dipeptides, which are efficient substrates for the synthesis of glutathione.[11] The minor component lactoferrin has received the most attention; it inhibits intestinal tumours and perhaps tumours at other sites.[14]

The SCD yogurt contains a very high amount of probiotics. Probiotics significantly decrease the levels of endotoxin(LPS). [15] Probiotic microorganisms have been shown to alter the composition of the intestinal microflora and thereby mediate anti-inflammatory effects. [16]

The goat milk does not contain the harmful casein that cow milk has. In any case, the yogurt-making process denatures the casein and renders it harmless.[17]

The Pecanbread list encourages parents to give lots of vegetables and fruits. This is a challenge because children with autism have a powerful tendency to have starch addiction and hate vegetables; unfortunately, parents have been warned that fruits cause yeast problems. Fortunately, many parents are surprised and delighted that their children are able to eat vegetables after starting SCD; this happens because their starch addiction has been conquered. If one transitions children with autism to the vegan diet some children will return to their old pattern of craving potatoes and rice and refuse to eat the green vegetables. This event would be more likely to happen to parents who do not get the support from individual nutritional counseling. We agree with Dr. Baker that vegetables are very important and want to continue encouraging the consumption of vegetables.

Some children need several years to recover from the brain damages caused by bacterial toxins. Parents who do SCD for many years report that the longer a child stays on SCD, the more healing occurs. Many of the children that Dr. Haas treated were on the autism spectrum but were less damaged than the children of today. For example, Dr. Haas described several symptoms of ASD but did not mention lack of speech and stims. When Dr. Haas wrote his book, there was less pollution, pesticides and food additives. The timeline for quitting SCD that is described in Elaine Gottschall's book is based on the work of Dr. Haas. It needs to be lengthened.

Does Campbell prove that meat is a risk factor for chronic diseases?

Most of the studies that Campbell presents involve the elimination of both meat and dairy, however, these studies do not definitively prove meat is bad since the suspected culprit is the milk. Since Campbell uses the huge survey gathered in China to impress readers, we need to focus closely on what actually was found there. There are at least two books about the "China Survey". The original one was published by Oxford University Press and contains raw data without any dietary advice or polemics.

Campbell uses the data for "animal proteins" gathered for China study in order to make conclusions to support a Vegan Diet. Nowhere in his book does he mention what the raw data was for meat consumption in the original study. Many websites (some of them by respected organizations such as the Weston Price Foundation)[18] have closely examined the data gathered in the original book published by Oxford University Press. The other websites report that the original survey from China does not prove that meat consumption leads to chronic illness. Chinese people are noted for their inability to digest lactose, so it is logical that a high consumption of "animal proteins" or "animal foods" would lead to chronic illness for Chinese people since the terms " animal foods" and "animal proteins" include cow's milk.

Campbell discusses the Chinese Survey in only one section of his book. He does write about other doctors who have removed both milk and meat from patients' diets. Their findings cannot be used to ban meat as long as milk might be the culprit. A few studies that Campbell cites contain results which cannot be explained without blaming milk. Close analysis reveals likely other factors beside meat.

Click here to examine this issue

PubMed
PubMed

References:

1. William L Stone1 , Min Qui1 and Milton Smith. Lipopolysaccharide enhances the cytotoxicity of 2-chloroethyl ethyl sulfide. BMC Cell Biology 2003, 4:1 doi:10.1186/1471-2121-4-1 View this article in biomedcentral

2. Blais DR, Vascotto SG, Griffith M, Altosaar I. LBP and CD14 secreted in tears by the lacrimal glands modulate the LPS response of corneal epithelial cells. Invest Ophthalmol Vis Sci. 2005;46(11):4235-44.

3. R.J. Ulevitch, V.V. Kravchenko, C. Fearns, T.-H. Chuang, J.C. Mathison, Q. Pan, J. da Silva Correia, K. Iwata, K.D. Janda, G. Kaufmann, M. Meijler. Molecular Mechanisms of Host-Pathogen Interactions. The Scripps Research Institute Website

4 Scientific American. July 2007 issue.

5. Shacter E, Weitzman SA. Chronic inflammation and cancer. Oncology (Williston Park). 2002 Feb;16(2):217-26, 229. View this article in PubMed
To read the full article: View entire Article

6. View Conference Website

7. Jyonouchi H , Sun S, Le H. Proinflammatory and regulatory cytokine production associated with innate and adaptive immune responses in children with autism. J Neuroimmunol. 2001 Nov 1;120(1-2):170-9. PubMed

8. Ma, Q., K. Kinneer. 2002. Chemoprotection by phenolic antioxidants: inhibition of tumor necrosis factor induction in macrophages. J. Biol. Chem. 277: 2477-2484. PubMed

9. Huang ST , Chen CT , Chieng KT, Huang SH, Chiang BH , Wang LF , Kuo HS, Lin CM. Inhibitory effects of a rice hull constituent on tumor necrosis factor alpha, prostaglandin E2, and cyclooxygenase-2 production in lipopolysaccharide-activated mouse macrophages. Ann N Y Acad Sci. 2005 May;1042:387-95. PubMed
Unfortunately, during the milling process, the hulls are removed from the grain to create brown rice.

10. Sabat� J. Nut consumption, vegetarian diets, ischemic heart disease risk, and all-cause mortality: evidence from epidemiologic studies. Am J Clin Nutr. 1999 Sep;70(3 Suppl):500S-503S. View this article in PubMed

11. Morris DD, Henry MM, Moore JN, Fischer K. Effect of dietary linolenic acid on endotoxin-induced thromboxane and prostacyclin production by equine peritoneal macrophages. Circ Shock. 1989 Dec;29(4):311-8. View this article in PubMed

12. Zhao G, Etherton TD, Martin KR, Gillies PJ, West SG, Kris-Etherton PM. Dietary alpha-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects. Am J Clin Nutr. 2007 Feb;85(2):385-91. . View this article in PubMed

13. Swallow DM. Genetics of lactase persistence and lactose intolerance. Annu Rev Genet. 2003;37:197-219.

14. Parodi PW. A Role for Milk Proteins and their Peptides in Cancer Prevention. Curr Pharm Des. 2007;13(8):813-28. PubMed

15. Shen TY, Qin HL, Gao ZG, Fan XB, Hang XM, Jiang YQ. Influences of enteral nutrition combined with probiotics on gut microflora and barrier function of rats with abdominal infection. World J Gastroenterol. 2006 Jul 21;12(27):4352-8. PubMed

16 .Gerbitz A, Schultz M, Wilke A, Linde HJ, Sch�lmerich J, Andreesen R, Holler E. Probiotic effects on experimental graft-versus-host disease: let them eat yogurt. Blood. 2004 Jun 1;103(11):4365-7. Epub 2004 Feb 12. PubMed

17. Adolfsson O, Meydani SN, Russell RM. Yogurt and gut function. 1: Am J Clin Nutr. 2004 Aug;80(2):245-56. In the "Protein" section of this article, the following statements were made: "It has been argued that protein from yogurt is more easily digested than is protein from milk, as bacterial predigestion of milk proteins in yogurt may occur" "During fermentation, both heat treatment and acid production result in finer coagulation of casein, which may also contribute to the greater protein digestibility of yogurt than of milk." View this article (The section called "Protein" contains information about how the proteins in yogurt are predigested by the lactic bacteria)

18. View the Weston A Price Foundation report about "The China Study".

Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet. 2001 Feb 17;357(9255):539-45. View this article in PubMed